Cytochrome C catalyzed oxygen tolerant atom-transfer radical polymerization

Abstract Atom-transfer radical polymerization (ATRP) is a well-known technique for controlled polymer synthesis. However, the ATRP usually employed toxic heavy metal ionas as catalyst and was susceptible to molecular oxygen, which made it should be conducted under strictly anoxic condition. Conducting ambient biocompatible conditions major challenge. In this study, cytochrome C explored an efficient biocatalyst conditions. The catalyzed showed relatively low dispersity index of 1.19. More interestingly, superior oxygen resistance could performed aerobic with high dissolved level. Further analysis suggested that Fe(II) embed in might serve catalytic center methyl responsible catalysis. This work new ATRP, open dimension practical application protein. Graphical